Presented by Gavin Esler
From the web team:
Tonight we'll have the latest on the news that 12 people have died from swine flu since Monday.
Our Economics Editor Paul Mason will be looking at the big problem that nobody knows the answer to: the double dip recession. Are we going to see it happen, and if not what will stop it? And, live from Tokyo, we hope to be speaking to economist-of-the-moment, Richard Koo, of the global finance house, Nomura.
"We must work globally both to establish the security conditions that will enable a world free from nuclear weapons," Gordon Brown said today in a statement on nuclear proliferation. However, it has also emerged that the government will delay a key spending decision on the replacement of the Trident missile system until after May 2010, in the hope of smoothing the way for the conference reviewing the Nuclear Non-Proliferation Treaty (NPT) scheduled for spring.
Meanwhile, the influential Commons Defence committee has warned that a shortage of helicopters is harming military operations in Afghanistan. There are clearly tough choices ahead on defence spending... but how should those choices be made, and what impact will they have on our national identity?
Plus, as the trial of pro-democracy leader Aung San Suu Kyi continues in Burma, we have film showing a rare glimpse of life in the military dictatorship and assessing the mood of the country's opposition movement.
Read more about tonight's film and watch some preview clips by clicking here.
We'll also be speaking to the best-selling children's novelist Antony Horowitz about a new law requiring anyone who has "regular" or "intense" contact with children or vulnerable adults to sign up to the Vetting and Barring Scheme at a cost of £64. Several other high-profile authors, including Philip Pullman have already announced that they will stop visiting schools in protest. We'll debate.
And, of course, forty years ago today, a little after half past nine in the morning, Neil Armstrong, Buzz Aldrin and Michael Collins blasted off from Cape Canaveral on board Apollo 11 on their mission to the moon. It was a historic moment that grabbed the attention of the United States and the world. When they safely arrived a few days later they had fulfilled President John F Kennedy's aim of reaching the moon by the end of the 1960s. In his famous speech given before a joint session of Congress on May 25th 1961, JFK had said:
"I believe that this nation should commit itself to achieving the goal, before this decade is out, of landing a man on the moon and returning him safely to the earth."
So what kind of challenge should we set for our generation? What similarly ambitious goal should we commit ourselves to achieving before a decade is out?
We'd like to hear your suggestions - leave your comments by clicking here.
Do join Gavin Esler for all that and more at 10.30pm on BBC Two. 
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